开心电玩城 - 百度买球指南

俞立

邮件：liyulab(at)mail(dot)tsinghua(dot)edu(dot)cn

研究方向:
综合细胞生物学，生物化学，系统生物学等手段，利用从酵母到小鼠等不同模式生物研究 1）自吞噬在细胞及分子水平上的调控机制 2）细胞程序性死亡3）细胞器的产生，运动的分子机制。

代表性科研论文:

1. Wu Y, Wang X, Guo H, Zhang B, Zhang XB, Shi ZJ*, Yu L*. Synthesis and screening of 3-MA derivatives for autophagy inhibitors. Autophagy. 2013 Apr 1;9(4):595-603.

2. Yueguang Rong, Mei Liu, Liang Ma, Wanqing Du, Hanshuo Zhang, Yuan Tian, Zhen Cao, Ying Li, He Ren, Chuanmao Zhang, Lin Li, She Chen, Jianzhong Xi^*&Li Yu^* Clathrin andphosphatidylinositol 4,5-bisphosphate regulate autophagic lysosome reformation. Nature Cell Biology, Sep;14(9):924-34

3. Cong Yi, Meisheng Ma, Leili Ran, Jingxiang Zheng, Jingjing Tong, Jing Zhu, Chengying Ma, YufenSun, ShaojinZhang, Wenzhi Feng, Liyuan Zhu, Yan Le, Xingqi Gong, Xianghua Yan, Bing Hong, Fen-Jun Jiang, Zhiping Xie, Di Miao,Haiteng Deng & Li Yu¹^* Function and molecular mechanism of acetylation in autophagy regulation. 2012 Apr 27, 474-477, Science.

4. Huang W, Choi W, Hu W, Mi N, Guo Q, Ma M, Liu M, Tian Y, Lu P, Wang FL, Deng H, Liu L, Gao N, Yu L*, Shi Y*. Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein. Cell Res. 2012 Feb 7

5. Ma X, Wu Y, Jin S, Tian Y, Zhang X, Zhao Y, Yu L*, Liang XJ*. Gold nanoparticles induce autophagosome accumulation through size-dependent nanoparticle uptake and lysosome impairment. ACS Nano. 2011 Nov 22;5(11):8629-39. Epub 2011 Oct 11.

6. Yueguang Rong , Christina K. McPhee, Shuangshen Deng , Lei Huang , Lilian Chen, Mei Liu, Kirsten Tracy, Eric H. Baehrecke, Li Yu* and Michael J. Lenardo, Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation. PNAS, 2011 Apr 25

7. Ye Tian, Zhipeng Li, Wanqiu Hu, Haiyan Ren, E Tian, Yu Zhao, Qun Lu, Xinxin Huang, Peiguo Yang, Xin Li, Xiaochen Wang, Attila L. Kovács, Li Yu*, and Hong Zhang*. C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms. Cell, 2010 Jun 11;141(6):1042-1055

8. Li Yu, Christina K. McPhee, Lixin Zheng, Gonzalo A. Mardones, Yueguang Rong, Junya Peng, Na Mi, Ying Zhao, Zhihua